Article
CD8+ regulatory T cells-A distinct T-cell lineage or a transient T-cell phenotype?
Human immunology - 1 Nov 2008
Aandahl Einar Martin, Torgersen Knut Martin, Taskén Kjetil
Abstract excerpt
Regulation of the immune system is fundamental for proper immune function and homeostasis. In the periphery, regulatory T cells provide self-tolerance and protect the host from harmful autoreactive T cells. Regulatory T cells are also involved in the pathogenesis of chronic viral infectious diseases and cancer. Both the CD4(+) and the CD8(+) T cell compartments contain regulatory T cells. Although various CD4(+)...
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