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Article

NCKX3 was compensated by calcium transporting genes and bone resorption in a NCKX3 KO mouse model.

Molecular and cellular endocrinology - 15 Oct 2017

Yang Hyun, Ahn Changhwan, Shin Eun-Kyeong, Lee Ji-Sun, An Beum-Soo, Jeung Eui-Bae

Abstract excerpt

Gene knockout is the most powerful tool for determination of gene function or permanent modification of the phenotypic characteristics of an animal. Existing methods for gene disruption are limited by their efficiency, time required for completion and potential for confounding off-target effects. In this study, a rapid single-step approach to knockout of a targeted gene in mice using zinc-finger nucleases (ZFNs)...

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Share to Bone Resorption
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28602864
DOI: 10.1016/j.mce.2017.06.006

Genes

TRPV5
TRPV6
VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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