Article
DHRS9 Is a Stable Marker of Human Regulatory Macrophages.
Transplantation - 1 Nov 2017
Riquelme Paloma, Amodio Giada, Macedo Camila, Moreau Aurelie, Obermajer Nataša, Brochhausen Christoph, Ahrens Norbert, Kekarainen Tuija, Fändrich Fred, Cuturi Cristina, Gregori Silvia, Metes Diana, Schlitt Hans J, Thomson Angus W, Geissler Edward K, Hutchinson James A
Abstract excerpt
BACKGROUND: The human regulatory macrophage (Mreg) has emerged as a promising cell type for use as a cell-based adjunct immunosuppressive therapy in solid organ transplant recipients. In this brief report, dehydrogenase/reductase 9 (DHRS9) is identified as a robust marker of human Mregs. METHODS: The cognate antigen of a mouse monoclonal antibody raised against human Mregs was identified as DHRS9 by...
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