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Article

Comparison of a New In-House and Three Published HLA-B*15:02 Screening Methods for Prevention of Carbamazepine-Induced Severe Drug Reactions.

PloS one - 1 Jan 2016

Jaruthamsophon Kanoot, Sripo Thanya, Sukasem Chonlaphat, Limprasert Pornprot

Abstract excerpt

Currently, there are three published HLA-B*15:02 screening methods for prevention of carbamazepine-induced severe drug reactions in Asian populations. To analyze available HLA-B*15:02 screening methods, we compared four screening methods, including a multiplex PCR method, a nested PCR method, a LAMP method and our new in-house PCR-dot blot hybridization method. These methods were reviewed regarding their...

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Source

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Identifiers

PMID: 27196420
DOI: 10.1371/journal.pone.0155907
PMCID: PMC4873226

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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