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Article

Clinical research in small genomically stratified patient populations.

European journal of cancer (Oxford, England : 1990) - 1 Jul 2017

Martin-Liberal J, Rodon J

Abstract excerpt

The paradigm of early drug development in cancer is shifting from 'histology-oriented' to 'molecularly oriented' clinical trials. This change can be attributed to the vast amount of tumour biology knowledge generated by large international research initiatives such as The Cancer Genome Atlas (TCGA) and the use of next generation sequencing (NGS) techniques developed in recent years. However, targeting infrequent...

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Identifiers

PMID: 28591680
DOI: 10.1016/j.ejca.2017.05.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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