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Article

Impact of Genomics on Personalized Cancer Medicine

31 Jan 2012

Abstract excerpt

Recent advances in tumor genetics and drug development have led to the generation of a wealth of anticancer targeted therapies. A few recent examples indicate that these drugs are mainly, if not exclusively, active against tumors of a particular genotype that can be identified by a diagnostic test, usually by detecting a somatic alteration in the tumor DNA. However, for the majority of targeted therapies in...

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PMID: 22298893
DOI: 10.1158/1078-0432.ccr-11-2019

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