Article
Implications of genome-wide association studies in cancer therapeutics.
British journal of clinical pharmacology - 1 Sept 2013
Patel Jai N, McLeod Howard L, Innocenti Federico
Abstract excerpt
Genome wide association studies (GWAS) provide an agnostic approach to identifying potential genetic variants associated with disease susceptibility, prognosis of survival and/or predictive of drug response. Although these techniques are costly and interpretation of study results is challenging, they do allow for a more unbiased interrogation of the entire genome, resulting in the discovery of novel genes and...
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