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Article

Genomic medicine frontier in human solid tumors: prospects and challenges.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 20 May 2013

Dienstmann Rodrigo, Rodon Jordi, Barretina Jordi, Tabernero Josep

Abstract excerpt

Recent discoveries of genomic alterations that underlie and promote the malignant phenotype, together with an expanded repertoire of targeted agents, have provided many opportunities to conduct hypothesis-driven clinical trials. The ability to profile each unique cancer for actionable aberrations by using high-throughput technologies in a cost-effective way provides unprecedented opportunities for using matched...

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PMID: 23589551
DOI: 10.1200/JCO.2012.45.2268

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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