Article
Gene-gene interactions among PPARα/δ/γ polymorphisms for hypertriglyceridemia in Chinese Han population.
Gene - 25 Feb 2013
Gu Shu-Jun, Liu Meng-Meng, Guo Zhi-Rong, Wu Ming, Chen Qiu, Zhou Zheng-Yuan, Zhang Li-Jun, Luo Wen-Shu
Abstract excerpt
The peroxisome proliferator-activated receptors (PPARs)-α,-β/δ and -γ are the ligand-activated transcription factors that function as the master regulators of glucose, fatty acid and lipoprotein metabolism, energy balance, cell proliferation and differentiation, inflammation and atherosclerosis. This study examined the main effects of both single-locus and multilocus interactions among genetic variants in Chinese...
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