Article
Distinct genomic signatures of adaptation in pre- and postnatal environments during human evolution.
Proceedings of the National Academy of Sciences of the United States of America - 4 Mar 2008
Uddin Monica, Goodman Morris, Erez Offer, Romero Roberto, Liu Guozhen, Islam Munirul, Opazo Juan C, Sherwood Chet C, Grossman Lawrence I, Wildman Derek E
Abstract excerpt
The human genome evolution project seeks to reveal the genetic underpinnings of key phenotypic features that are distinctive of humans, such as a greatly enlarged cerebral cortex, slow development, and long life spans. This project has focused predominantly on genotypic changes during the 6-million-year descent from the last common ancestor (LCA) of humans and chimpanzees. Here, we argue that adaptive genotypic...
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