Article
Systemic evolutionary changes in mammalian gene expression.
Bio Systems - 1 Dec 2020
Vinogradov Alexander E, Anatskaya Olga V
Abstract excerpt
Changes in gene expression play an important role in evolution and can be relevant to evolutionary medicine. In this work, a strong relationship was found between the statistical significance of evolutionary changes in the expression of orthologous genes in the five or six homologous mammalian tissues and the across-tissues unidirectionality of changes (i.e., they occur in the same direction in different tissues...
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