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Article

BMP signaling orchestrates a transcriptional network to control the fate of mesenchymal stem cells in mice

2 Jun 2017

Abstract excerpt

Signaling pathways are used reiteratively in different developmental processes yet produce distinct cell fates through specific downstream transcription factors. In this study, we used tooth root development as a model with which to investigate how the BMP signaling pathway regulates transcriptional complexes to direct the fate determination of multipotent mesenchymal stem cells (MSCs). We first identified the...

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PMID: 28576771
DOI: 10.1242/dev.150136

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