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Article

Knockdown of FOXA1 enhances the osteogenic differentiation of human bone marrow mesenchymal stem cells partly via activation of the ERK1/2 signalling pathway

2022-06-10

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> The available therapeutic options for large bone defects remain extremely limited, requiring new strategies to accelerate bone healing. Genetically modified bone mesenchymal stem cells (BMSCs) with enhanced osteogenic capacity are recognised as one of the most promising treatments for bone defects.<bold>Method:</bold> We performed differential expression analysi...

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Literature Corpus work
14e26f33-4804-5a43-ba93-42bab074fb5b
DOI
10.21203/rs.3.rs-1718532/v1
Open publication

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Knockdown of FOXA1 enhances the osteogenic differentiation of human bone marrow mesenchymal stem cells partly via activation of the ERK1/2 signalling pathwayDOI 10.21203/rs.3.rs-1718532/v1
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