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Article

The developmental regulator PKL is required to maintain correct DNA methylation patterns at RNA-directed DNA methylation loci.

Genome biology - 31 May 2017

Yang Rong, Zheng Zhimin, Chen Qing, Yang Lan, Huang Huan, Miki Daisuke, Wu Wenwu, Zeng Liang, Liu Jun, Zhou Jin-Xing, Ogas Joe, Zhu Jian-Kang, He Xin-Jian, Zhang Heng

Abstract excerpt

BACKGROUND: The chromodomain helicase DNA-binding family of ATP-dependent chromatin remodeling factors play essential roles during eukaryote growth and development. They are recruited by specific transcription factors and regulate the expression of developmentally important genes. Here, we describe an unexpected role in non-coding RNA-directed DNA methylation in Arabidopsis thaliana. RESULTS: Through forward...

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Arabidopsis
DNA-Directed RNA Polymerases
DNA Methylation
Gene Expression Regulation, Plant
Gene Silencing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

RNA, Small Interfering

RNA, Untranslated

Transcription, Genetic

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PMID: 28569170
DOI: 10.1186/s13059-017-1226-y
PMCID: PMC5452414

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