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Article

STAT3 signaling in immunity.

Cytokine & growth factor reviews - 1 Oct 2016

Hillmer Emily J, Zhang Huiyuan, Li Haiyan S, Watowich Stephanie S

Abstract excerpt

The transcriptional regulator STAT3 has key roles in vertebrate development and mature tissue function including control of inflammation and immunity. Mutations in human STAT3 associate with diseases such as immunodeficiency, autoimmunity and cancer. Strikingly, however, either hyperactivation or inactivation of STAT3 results in human disease, indicating tightly regulated STAT3 function is central to health....

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Source

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Identifiers

PMID: 27185365
DOI: 10.1016/j.cytogfr.2016.05.001
PMCID: PMC5050093

Genes

STAT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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