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Article

Genetically-defined novel oral squamous cell carcinoma cell lines for the development of molecular therapies.

Oncotarget - 10 May 2016

Fadlullah Muhammad Zaki Hidayatullah, Chiang Ivy Kim-Ni, Dionne Kalen R, Yee Pei San, Gan Chai Phei, Sam Kin Kit, Tiong Kai Hung, Ng Adrian Kwok Wen, Martin Daniel, Lim Kue Peng, Kallarakkal Thomas George, Mustafa Wan Mahadzir Wan, Lau Shin Hin, Abraham Mannil Thomas, Zain Rosnah Binti, Rahman Zainal Ariff Abdul, Molinolo Alfredo, Patel Vyomesh, Gutkind J Silvio, Tan Aik Choon, Cheong Sok Ching

Abstract excerpt

Emerging biological and translational insights from large sequencing efforts underscore the need for genetically-relevant cell lines to study the relationships between genomic alterations of tumors, and therapeutic dependencies. Here, we report a detailed characterization of a novel panel of clinically annotated oral squamous cell carcinoma (OSCC) cell lines, derived from patients with diverse ethnicity and risk...

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Identifiers

PMID: 27050151
DOI: 10.18632/oncotarget.8533
PMCID: PMC5053689

Genes

ARID2
CASP8
CDK1
EPHA2
FAT1
NOTCH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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