Article
Altered molecular profile in thyroid cancers from patients affected by the Three Mile Island nuclear accident.
The Laryngoscope - 1 Jul 2017
Goldenberg David, Russo Mariano, Houser Kenneth, Crist Henry, Derr Jonathan B, Walter Vonn, Warrick Joshua I, Sheldon Kathryn E, Broach James, Bann Darrin V
Abstract excerpt
OBJECTIVES/HYPOTHESIS: In 1979, Three Mile Island (TMI) nuclear power plant experienced a partial meltdown with release of radioactive material. The effects of the accident on thyroid cancer (TC) in the surrounding population remain unclear. Radiation-induced TCs have a lower incidence of single nucleotide oncogenic driver mutations and higher incidence of gene fusions. We used next generation sequencing (NGS) to...
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