Genomic characterization of cervical lymph node metastases in papillary thyroid carcinoma following the Chornobyl accident.

doi:10.1038/s41467-024-49292-z

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Article

Genomic characterization of cervical lymph node metastases in papillary thyroid carcinoma following the Chornobyl accident.

Nature communications - 13 Jun 2024

Morton Lindsay M, Lee Olivia W, Karyadi Danielle M, Bogdanova Tetiana I, Stewart Chip, Hartley Stephen W, Breeze Charles E, Schonfeld Sara J, Cahoon Elizabeth K, Drozdovitch Vladimir, Masiuk Sergii, Chepurny Mykola, Zurnadzhy Liudmyla Yu, Dai Jieqiong, Krznaric Marko, Yeager Meredith, Hutchinson Amy, Hicks Belynda D, Dagnall Casey L, Steinberg Mia K, Jones Kristine, Jain Komal, Jordan Ben, Machiela Mitchell J, Dawson Eric T, Vij Vibha, Gastier-Foster Julie M, Bowen Jay, Mabuchi Kiyohiko, Hatch Maureen, Berrington de Gonzalez Amy, Getz Gad, Tronko Mykola D, Thomas Gerry A, Chanock Stephen J

Abstract excerpt

Childhood radioactive iodine exposure from the Chornobyl accident increased papillary thyroid carcinoma (PTC) risk. While cervical lymph node metastases (cLNM) are well-recognized in pediatric PTC, the PTC metastatic process and potential radiation association are poorly understood. Here, we analyze cLNM occurrence among 428 PTC with genomic landscape analyses and known drivers (131I-exposed = 349, unexposed =...

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Share to Chernobyl Nuclear Accident

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 38871684
DOI: 10.1038/s41467-024-49292-z
PMCID: PMC11176192

Genes

BRAF
BRINP3
HOXC10
RET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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