Article

Mutational footprint of platinum chemotherapy in a secondary thyroid cancer

2022-03-15

Abstract excerpt

Although papillary thyroid carcinoma (PTC) is the most frequent endocrine tumor with a generally excellent prognosis, a patient developed a clinically aggressive PTC eleven years after receiving platinum chemotherapy for ovarian endometrioid adenocarcinoma. Germline and somatic analyses of multi-temporal and multi-regional molecular profiles indicated that ovarian and thyroid tumors did not share common genetic al...

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Literature Corpus work: 5b5afe31-55a6-59fd-a78a-4652e3d6f9c6
DOI: 10.1101/2022.03.14.484002

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