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Article

Investigation of the Relationship Between Radiation Dose and Gene Mutations and Fusions in Post-Chernobyl Thyroid Cancer.

Journal of the National Cancer Institute - 1 Apr 2018

Efanov Alexey A, Brenner Alina V, Bogdanova Tetiana I, Kelly Lindsey M, Liu Pengyuan, Little Mark P, Wald Abigail I, Hatch Maureen, Zurnadzy Liudmyla Y, Nikiforova Marina N, Drozdovitch Vladimir, Leeman-Neill Rebecca, Mabuchi Kiyohiko, Tronko Mykola D, Chanock Stephen J, Nikiforov Yuri E

Abstract excerpt

Background: Exposure to ionizing radiation during childhood is a well-established risk factor for thyroid cancer. However, the genetic mechanisms of radiation-associated carcinogenesis remain not fully understood. Methods: In this study, we used targeted next-generation sequencing and RNA-Seq to study 65 papillary thyroid cancers (PTCs) from patients in the Ukrainian-American cohort with measurement-based...

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Source

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Identifiers

PMID: 29165687
DOI: 10.1093/jnci/djx209
PMCID: PMC6059206

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ALK
BRAF
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STRN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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