Article
TERT and BRAF V600E mutations in thyroid cancer of World Trade Center Responders.
Carcinogenesis - 24 Jun 2023
van Gerwen Maaike, Cerutti Janete Maria, Mendes Thais Biude, Brody Rachel, Genden Eric, Riggins Gregory J, Taioli Emanuela
Abstract excerpt
The 2-fold excess thyroid cancer risk reported in multiple World Trade Center (WTC) disaster exposed cohorts cannot entirely be explained by surveillance and physician bias thus highlighting the need to investigate the potential consequences of the dust exposure, containing carcinogenic and endocrine disruptive elements, on the thyroid. This study investigated the presence of TERT promoter and BRAF V600E...
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