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Genomic and phenotypic inconsistencies in Pseudomonas aeruginosa resistome among intensive care patients.

Frontiers in cellular and infection microbiology - 1 Jan 2024

Dolgusevs Mihails, Jain Nityanand, Savicka Oksana, Vangravs Reinis, Bodrenko Jevgenijs, Bergmanis Edvins, Zemite Dace, Selderina Solvita, Reinis Aigars, Rozentale Baiba

Abstract excerpt

Objective: Pseudomonas aeruginosa, a difficult-to-manage nosocomial pathogen, poses a serious threat to clinical outcomes in intensive care (ICU) patients due to its high antimicrobial resistance (AMR). To promote effective management, it is essential to investigate the genomic and phenotypic differences in AMR expression of the isolates. Methods: A prospective observational study was conducted from July 2022 to...

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PMID: 38975326
DOI: 10.3389/fcimb.2024.1335096
PMCID: PMC11224958

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