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Molecular determinants associated with resistance to imipenem and imipenem–relebactam in clinical Pseudomonas aeruginosa isolates

2025-11-04

Abstract excerpt

<title>Abstract</title> <p> Background <italic>Pseudomonas aeruginosa</italic> accounts for 10–20% of hospital-acquired infections and is a major pathogen in immunocompromised patients. Combination therapies with beta-lactam antibiotics and beta-lactamase inhibitors, such as imipenem-relebactam have improved treatment options, yet resistant strains have already emerged, with mechanisms still not fully elucidat...

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Literature Corpus work
8501ed0f-1962-5adf-9bf6-b71bf6f2ef04
DOI
10.21203/rs.3.rs-7801871/v1
Open publication

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