Article
Comparative genomics of a drug-resistant Pseudomonas aeruginosa panel and the challenges of antimicrobial resistance prediction from genomes.
FEMS microbiology letters - 2 Oct 2017
Jeukens J, Kukavica-Ibrulj I, Emond-Rheault J G, Freschi L, Levesque R C
Abstract excerpt
Antimicrobial resistance (AMR) is now recognized as a global threat to human health. The accessibility of microbial whole-genome sequencing offers an invaluable opportunity for resistance surveillance via the resistome, i.e. the genes and mutations underlying AMR. Unfortunately, AMR prediction from genomic data remains extremely challenging, especially for species with a large pan-genome. One such organism, for...
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