Article
The CNDP1 (CTG)5 Polymorphism Is Associated with Biopsy-Proven Diabetic Nephropathy, Time on Hemodialysis, and Diabetes Duration.
Journal of diabetes research - 1 Jan 2017
Albrecht Thomas, Zhang Shiqi, Braun Jana D, Xia Li, Rodriquez Angelica, Qiu Jiedong, Peters Verena, Schmitt Claus P, van den Born Jacob, Bakker Stephan J L, Lammert Alexander, Köppel Hannes, Schnuelle Peter, Krämer Bernhard K, Yard Benito A, Hauske Sibylle J
Abstract excerpt
Considering that the homozygous CNDP1 (CTG)5 genotype affords protection against diabetic nephropathy (DN) in female patients with type 2 diabetes, this study assessed if this association remains gender-specific when applying clinical inclusion criteria (CIC-DN) or biopsy proof (BP-DN). Additionally, it assessed if the prevalence of the protective genotype changes with diabetes duration and time on hemodialysis...
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