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Article

Analysis of PIK3CA mutations and PI3K pathway proteins in advanced gastric cancer.

The Journal of surgical research - 15 May 2017

Ito Chie, Nishizuka Satoshi S, Ishida Kazuyuki, Uesugi Noriyuki, Sugai Tamotsu, Tamura Gen, Koeda Keisuke, Sasaki Akira

Abstract excerpt

BACKGROUND: Although surgery and chemotherapy have extended advanced gastric cancer patient survival, some patients still experience relapse and metastasis. We postulated that PI3K pathway proteins could be prognostic biomarkers for the advanced gastric cancer patients. METHODS: A retrospective cohort of 160 advanced gastric cancer patients receiving potentially curative surgery with/without chemotherapy was...

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Identifiers

PMID: 28550907
DOI: 10.1016/j.jss.2017.01.018

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