Article
Type 1 diabetes increases retention of low-density lipoprotein in the atherosclerosis-prone area of the murine aorta.
Atherosclerosis - 1 Aug 2017
Hagensen Mette K, Mortensen Martin Bødtker, Kjolby Mads, Stillits Ninna L, Steffensen Lasse B, Bentzon Jacob F
Abstract excerpt
BACKGROUND AND AIMS: Individuals with type 1 diabetes mellitus are at high risk of developing atherosclerotic cardiovascular disease, but the underlying mechanisms by which type 1 diabetes accelerates atherosclerosis remain unknown. Increased retention of low-density lipoprotein (LDL) in atherosclerosis-prone sites of the diabetic vascular wall has been suggested, but direct evidence is lacking. In the present...
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