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Article

APOE ε4 Modulation of Training Outcomes in Several Cognitive Domains in a Sample of Cognitively Intact Older Adults.

Journal of Alzheimer's disease : JAD - 1 Jan 2017

López-Higes Ramón, Rodríguez-Rojo Inmaculada C, Prados José M, Montejo Pedro, Del-Río David, Delgado-Losada María Luisa, Montenegro Mercedes, López-Sanz David, Barabash Ana

Abstract excerpt

BACKGROUND: Most research points to the ɛ4 allele of the apolipoprotein E (APOE) gene as the most recognizable genetic risk factor associated with Alzheimer's disease pathogenesis. It has been also suggested that the APOEɛ4 allele has a negative influence on cognitive functioning, which begins long before cognitive impairment becomes manifest. However, still, little is known about the APOEɛ4 interaction with...

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Identifiers

PMID: 28550244
DOI: 10.3233/JAD-161014

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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