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Article

Interactions between physical exercise, associative memory, and genetic risk for Alzheimer's disease.

Cerebral cortex (New York, N.Y. : 1991) - 2 May 2024

Igloi Kinga, Marin Bosch Blanca, Kuenzi Noémie, Thomas Aurélien, Lauer Estelle, Bringard Aurélien, Schwartz Sophie

Abstract excerpt

The ε4 allele of the APOE gene heightens the risk of late onset Alzheimer's disease. ε4 carriers, may exhibit cognitive and neural changes early on. Given the known memory-enhancing effects of physical exercise, particularly through hippocampal plasticity via endocannabinoid signaling, here we aimed to test whether a single session of physical exercise may benefit memory and underlying neurophysiological...

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Identifiers

PMID: 38802684
DOI: 10.1093/cercor/bhae205
PMCID: PMC11129939

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