Article
Impact of APOE status on cognitive maintenance in healthy elderly persons.
International journal of geriatric psychiatry - 1 Feb 2009
Zehnder Antoinette E, Bläsi Stefan, Berres Manfred, Monsch Andreas U, Stähelin Hannes B, Spiegel René
Abstract excerpt
OBJECTIVE: The epsilon4 allele, a variant of the apolipoprotein E (ApoE) gene, is the most prominent genetic risk factor for sporadic, non-familial Alzheimer's disease (AD) currently known. We investigated the impact of the ApoE-epsilon4 status on cognitive performance at repeated test administration in elderly non-symptomatic persons, with a specific focus on practice effects. METHODS: Three hundred and...
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