Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dual redundant sequencing strategy: Full-length gene characterisation of 1056 novel and confirmatory HLA alleles.

HLA - 1 Aug 2017

Albrecht V, Zweiniger C, Surendranath V, Lang K, Schöfl G, Dahl A, Winkler S, Lange V, Böhme I, Schmidt A H

Abstract excerpt

The high-throughput department of DKMS Life Science Lab encounters novel human leukocyte antigen (HLA) alleles on a daily basis. To characterise these alleles, we have developed a system to sequence the whole gene from 5'- to 3'-UTR for the HLA loci A, B, C, DQB1 and DPB1 for submission to the European Molecular Biology Laboratory - European Nucleotide Archive (EMBL-ENA) and the IPD-IMGT/HLA Database. Our...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Databases, Nucleic Acid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Loci

Share to High-Throughput Nucleotide Sequencing

Share to HLA Antigens

Source

Open in PubMed Open full text

Identifiers

PMID: 28547825
DOI: 10.1111/tan.13057
PMCID: PMC6084308

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dual redundant sequencing strategy: Full-length gene characterisation of 1056 novel and confirmatory HLA alleles.PMID 28547825Read ↗

Full-Length Characterization of Novel HLA-DRB1 Alleles for Reference Database Submission.Semantic proximity Read ↗

High-throughput, high-fidelity HLA genotyping with deep sequencing.Semantic proximity Read ↗

High-throughput next-generation sequencing to genotype six classical HLA loci from 96 donors in a single MiSeq run.Semantic proximity Read ↗

Filling the gaps - the generation of full genomic sequences for 15 common and well-documented HLA class I alleles using next-generation sequencing technology.Semantic proximity Read ↗

Progressing towards the complete and thorough characterization of the HLA genes by NGS (or single-molecule DNA sequencing): Consequences, opportunities and challengesSemantic proximity Read ↗

Description of a modified sequencing strategy and the molecular characterization of HLA-B*8201.Semantic proximity Read ↗

Widespread non-coding polymorphism in HLA class II genes of International HLA and Immunogenetics Workshop cell lines.Semantic proximity Read ↗

Complete sequences of six major histocompatibility complex haplotypes, including all the major MHC class II structures.Semantic proximity Read ↗

Single molecule real-time DNA sequencing of HLA genes at ultra-high resolution from 126 International HLA and Immunogenetics Workshop cell lines.Semantic proximity Read ↗

NovAT tool-Reliable novel HLA alleles identification from next-generation sequencing data.Semantic proximity Read ↗

Recent Advances of Human Leukocyte Antigen (HLA) Typing Technology Based on High-Throughput Sequencing.Semantic proximity Read ↗

2.7 million samples genotyped for HLA by next generation sequencing: lessons learned.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.