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Article

Full-Length Characterization of Novel HLA-DRB1 Alleles for Reference Database Submission.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2024

Putke Kathrin, Albrecht Viviane, Paech Christin, Pahlke Madlen, Schöne Bianca, Klasberg Steffen, Schmidt Alexander H, Lange Vinzenz, Schöfl Gerhard, Klussmeier Anja

Abstract excerpt

The prerequisite for successful HLA genotyping is the integrity of the large allele reference database IPD-IMGT/HLA. Consequently, it is in the laboratories' best interest that the data quality of submitted novel sequences is high. However, due to its long and variable length, the gene HLA-DRB1 presents the biggest challenge and as of today only 16% of the HLA-DRB1 alleles in the database are characterized in...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 38907896
DOI: 10.1007/978-1-0716-3874-3_10

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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