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Article

p62/sequestosome 1 in human colorectal carcinoma as a potent prognostic predictor associated with cell proliferation

23 May 2017

Abstract excerpt

p62/sequestosome 1 (p62) is a multi-domain protein that functions as a receptor for ubiquitinated targets in the selective autophagy and serves as a scaffold in various signaling cascades. p62 have been reported to be up-regulated in several human malignancies, but the biological roles and significance of p62 are still poorly understood in colorectal carcinoma. We immunohistochemically evaluated p62 in 118...

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PMID: 28544335
DOI: 10.1002/cam4.1093

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