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Sequestosome 1/p62: A multitasker in the regulation of malignant tumor aggression (Review)

18 Aug 2021

Abstract excerpt

Sequestosome 1 (SQSTM1)/p62 is an adapter protein mainly involved in the transportation, degradation and destruction of various proteins that cooperates with components of autophagy and the ubiquitin‑proteasome degradation pathway. Numerous studies have shown that SQSTM1/p62 functions at multiple levels, including involvement in genetic stability or modification, post‑transcriptional regulation and protein...

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PMID: 34414460
DOI: 10.3892/ijo.2021.5257

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