Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Overexpression of p62/IMP2 can Promote Cell Migration in Hepatocellular Carcinoma via Activation of the Wnt/β-Catenin Pathway

18 Dec 2019

Abstract excerpt

p62/IMP2 is an oncofetal protein that was first reported as a tumor-associated antigen in hepatocellular carcinoma (HCC). In our previous studies, we demonstrated a high frequency of p62/IMP2 autoantibodies appearing in various types of cancer. Therefore, we hypothesize that p62/IMP2 plays an important role in the progression of HCC, although the mechanism remains to be explored. In this study, we evaluated the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Research and Treatments
Share to Peptidase Inhibition and Analysis
Share to RNA modifications and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31861402
DOI: 10.3390/cancers12010007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Overexpression of p62/IMP2 can Promote Cell Migration in Hepatocellular Carcinoma via Activation of the Wnt/β-Catenin PathwayPMID 31861402Read ↗

IMP2/p62 induces genomic instability and an aggressive hepatocellular carcinoma phenotype.Semantic proximity Read ↗

p62/IMP2 stimulates cell migration and reduces cell adhesion in breast cancerSemantic proximity Read ↗

Oncofetal Protein IMP3, a New Cancer BiomarkerSemantic proximity Read ↗

TP53BP2: Roles in suppressing tumorigenesis and therapeutic opportunitiesSemantic proximity Read ↗

Elevated expression of the <i>IGF2</i> mRNA binding protein 2 (IGF2BP2/IMP2) is linked to short survival and metastasis in esophageal adenocarcinomaSemantic proximity Read ↗

MARCH5 promotes autophagy through interaction with P62 leading to malignant progression of hepatocellular carcinomaSemantic proximity Read ↗

MFAP2 Promotes the Proliferation of Cancer Cells and Is Associated With a Poor Prognosis in Hepatocellular Carcinoma.Semantic proximity Read ↗

Inhibition of WWP2 suppresses proliferation, and induces G1 cell cycle arrest and apoptosis in liver cancer cellsSemantic proximity Read ↗

WWP1 upregulation predicts poor prognosis and promotes tumor progression by regulating ubiquitination of NDFIP1 in intrahepatic cholangiocarcinomaSemantic proximity Read ↗

A novel function of IMPA2, plays a tumor-promoting role in cervical cancerSemantic proximity Read ↗

UBE2S enhances the ubiquitination of p53 and exerts oncogenic activities in hepatocellular carcinomaSemantic proximity Read ↗

MTBP inhibits the Erk1/2-Elk-1 signaling in hepatocellular carcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.