Article
The Association of Mitofusion-2 Gene Polymorphisms with Susceptibility of Essential Hypertension in Northern Han Chinese Population.
International journal of medical sciences - 1 Jan 2016
Li Mei, Zhang Bei, Li Chuang, Liu Jielin, Liu Ya, Sun Dongdong, Ma Hanying, Wen Shaojun
Abstract excerpt
BACKGROUND: Mitofusion-2 (Mfn2) played an important role in regulating vascular smooth muscle cells proliferation, insulin resistance and endoplasmic reticulum stress, which were found to be involved in the development of hypertension. So we inferred that the Mfn2 gene may participate in the pathogenesis of hypertension. The aim of this study was to determine whether common single nucleotide polymorphisms (SNPs)...
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