Article
Association of PD-1.5 C/T, but Not PD-1.3 G/A, with Malignant and Benign Brain Tumors in Iranian Patients.
Immunological investigations - 1 Jul 2017
Namavar Jahromi Fatemeh, Samadi Morteza, Mojtahedi Zahra, Haghshenas Mohammad Reza, Taghipour Mosa, Erfani Nasrollah
Abstract excerpt
Programmed death-1 (PD-1) negatively regulates the immune response. The aims of this study were to assess the association of two single nucleotide polymorphisms in the PD-1 gene, PD-1.5 (+7785 C/T-rs2227981) and PD-1.3 (+7146 G/A- rs11568821), with benign and malignant brain tumors. Patients with brain tumors (96 patients with benign and 56 with malignant brain tumors) and 150 healthy control individuals were...
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