Association of programmed cell death 1 (PD-1) gene polymorphism (rs10204525) with COVID-19 severity and mortality: A case-control study in the Iranian population.

doi:10.1016/j.intimp.2023.110114

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Association of programmed cell death 1 (PD-1) gene polymorphism (rs10204525) with COVID-19 severity and mortality: A case-control study in the Iranian population.

International immunopharmacology - 1 Jun 2023

Mirsharif Ensie Sadat, Rostamian Abdolrahman, Salehi Mohammadreza, Askari Nayere, Ghazanfari Tooba

Abstract excerpt

BACKGROUND: Programmed cell death 1 (PD-1), as a negative immune regulator, regulates the activation of T cells and maintains the immune system's homeostasis. Previous studies suggest that the effective immune response against COVID-19 contributes to the outcome of the disease. The present study aims to evaluate whether the PD-1 rs10204525 polymorphism is associated with PDCD-1 expression and COVID-19 severity...

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Identifiers

PMID: 37172423
DOI: 10.1016/j.intimp.2023.110114
PMCID: PMC10063540

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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