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Article

hTERT C250T promoter mutation and telomere length as a molecular markers of cancer progression in patients with head and neck cancer.

Molecular medicine reports - 1 Jul 2017

Barczak Wojciech, Suchorska Wiktoria M, Sobecka Agnieszka, Bednarowicz Karolina, Machczynski Piotr, Golusinski Pawel, Rubis Blazej, Masternak Michal M, Golusinski Wojciech

Abstract excerpt

Squamous cell carcinoma of the head and neck (HNSCC) is the sixth leading cause of cancer worldwide, representing over half a million incidents every year. Cancer cells, including HNSCC, are characterized by increased telomerase activity. This enzymatic complex is active in ~90% of all cancer types and is responsible for the lengthening of telomeres. Highly recurrent point mutations in the human telomerase...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28535013
DOI: 10.3892/mmr.2017.6590

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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