Article
Genetic variations associated with telomere length predict the risk of recurrence of non-oropharyngeal head and neck squamous cell carcinoma.
Molecular carcinogenesis - 1 Sept 2024
Sun Peng, Gu Kyle J, Zheng Guibin, Sikora Andrew G, Li Chao, Zafereo Mark, Wei Peng, Wu Jia, Shete Sanjay, Liu Jisheng, Li Guojun
Abstract excerpt
Genetic factors underlying lymphocyte telomere length (LTL) may provide insights into genomic stability and integrity, with direct links to susceptibility to cancer recurrence. Polymorphisms in telomere-associated genes are strongly associated with LTL and cancer risk, while few large studies have explored the associations between LTL-related polymorphisms and recurrence risk of non-oropharyngeal head and neck...
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