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Article

Strong association of CTLA-4 variation (CT60A/G) and CTLA-4 haplotypes with predisposition of Iranians to head and neck cancer.

Iranian journal of immunology : IJI - 1 Sept 2012

Erfani Nasrollah, Haghshenas Mohammad Reza, Hoseini Mohammad Ali, Hashemi Seyed Basir, Khademi Bijan, Ghaderi Abbas

Abstract excerpt

BACKGROUND: Variations in Cytotoxic T Lymphocyte Antigen-4 (CTLA-4) affect the expression and function of this protein. OBJECTIVE: We aimed to investigate the association of +49 A/G (rs231775), +1822 C/T (rs231779) and +6230 A/G (CT60, rs3087243) genetic variations, as well as the merged haplotypes in CTLA-4 gene with susceptibility to, or progression of head and neck cancer. METHODS: Eighty patients with...

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Identifiers

PMID: 23023383
DOI: 10.22034/iji.2012.16871

Genes

GCA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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