Article
Influence of Transmitted Virus on the Host's Immune Response: A Case Study.
Viral immunology - 1 Sept 2017
Merani Shahzma, Lucas Michaela, Deshpande Pooja, Pfafferott Katja, Chopra Abha, Cooper Don, Leary Shay, Luciani Fabio, Gaudieri Silvana
Abstract excerpt
Host hepatitis C virus (HCV)-specific T cell responses and the ability of the virus to escape this response are important correlates of infection outcome. Understanding this host-viral interplay has been difficult given the often asymptomatic nature of acute HCV infection. We studied a recent transmission case to determine whether adapted viral strains can be transmitted and influence the recipient's anti-HCV T...
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