Article
A novel double kink-turn module in euryarchaeal RNase P RNAs.
Nucleic acids research - 7 Jul 2017
Lai Lien B, Tanimoto Akiko, Lai Stella M, Chen Wen-Yi, Marathe Ila A, Westhof Eric, Wysocki Vicki H, Gopalan Venkat
Abstract excerpt
RNase P is primarily responsible for the 5΄ maturation of transfer RNAs (tRNAs) in all domains of life. Archaeal RNase P is a ribonucleoprotein made up of one catalytic RNA and five protein cofactors including L7Ae, which is known to bind the kink-turn (K-turn), an RNA structural element that causes axial bending. However, the number and location of K-turns in archaeal RNase P RNAs (RPRs) are unclear. As part of...
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