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Article

Insight into the functional role of unique determinants in RNA component of RNase P of Mycobacterium tuberculosis.

International journal of biological macromolecules - 1 Nov 2018

Singh Alla, Batra Janendra K

Abstract excerpt

RNase P, an essential ribonucleoprotein enzyme is involved in processing 5' end of pre-tRNA molecules. All bacterial RNase P holoenzymes, including that of Mycobacterim tuberculosis, an important human pathogen contain a catalytically active RNA subunit and a protein subunit. However, the mycobacterial RNA is larger than typical bacterial RNase P RNAs. It contains the essential core structure and many unique...

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PMID: 30086331
DOI: 10.1016/j.ijbiomac.2018.08.013

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