Article
Colorectal cancer in Crohn's colitis is comparable to sporadic colorectal cancer.
International journal of colorectal disease - 1 May 2016
Lennerz Jochen K, van der Sloot Kimberley W J, Le Long Phi, Batten Julie M, Han Jae Young, Fan Kenneth C, Siegel Corey A, Srivastava Amitabh, Park Do Youn, Chen Jey-Hsin, Sands Bruce E, Korzenik Joshua R, Odze Robert D, Dias-Santagata Dora, Borger Darrell R, Khalili Hamed, Iafrate A John, Lauwers Gregory Y
Abstract excerpt
PURPOSE: It is now recognized that Crohn's disease (CD), similar to ulcerative colitis (UC), carries an up to 20-fold higher cancer risk, and the development of colorectal carcinoma (CRC) is a major long-term complication. Once CRC is present, molecular profiling is one of the components in selecting appropriate treatment strategies; however, in contrast to UC, genetic alterations in Crohn's colitis-associated...
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