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Article

Effective antimicrobial activity of a peptide mutant Cbf-14-2 against penicillin-resistant bacteria based on its unnatural amino acids.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences - 15 Jul 2017

Kang Wei, Liu Hanhan, Ma Lingman, Wang Mengxiao, Wei Shanshan, Sun Pengbo, Jiang Meiling, Guo Min, Zhou Changlin, Dou Jie

Abstract excerpt

Broad spectrum activities, a unique mode of actions and rare resistant variants make antimicrobial peptide (AMP) a potential alternative to antibiotics. However, AMPs still have limitations in clinical development due to their physiological stability, toxicity and manufacturing costs. Cbf-14, derived from cathelicidin-BF has been proven to be effective against drug-resistant bacteria. Herein, a series of Cbf-14...

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PMID: 28522372
DOI: 10.1016/j.ejps.2017.05.030

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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