Article
Novel Antimicrobial Peptides from a Cecropin-Like Region of Heteroscorpine-1 from Heterometrus laoticus Venom with Membrane Disruption Activity.
Molecules (Basel, Switzerland) - 28 Sept 2021
Erviana Rima, Saengkun Yutthakan, Rungsa Prapenpuksiri, Jangpromma Nisachon, Tippayawat Patcharaporn, Klaynongsruang Sompong, Daduang Jureerut, Daduang Sakda
Abstract excerpt
The increasing antimicrobial-resistant prevalence has become a severe health problem. It has led to the invention of a new antimicrobial agent such as antimicrobial peptides. Heteroscorpine-1 is an antimicrobial peptide that has the ability to kill many bacterial strains. It consists of 76 amino acid residues with a cecropin-like region in N-terminal and a defensin-like region in the C-terminal. The cecropin-like...
Topics
- Amino Acid Sequence
- Animals
- Cecropins
- Cell Membrane
- Insect Proteins
- Mutation
- Pore Forming Cytotoxic Proteins
- Scorpion Venoms
- Scorpions
- Sequence Homology