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Article

Prevalence of relevant NS5A resistance-associated substitutions to elbasvir in genotype 1a hepatitis C virus patients in Spain.

Enfermedades infecciosas y microbiologia clinica (English ed.) - 1 May 2018

Palladino Claudia, Esteban-Cartelle Beatriz, Mate-Cano Irene, Sánchez-Carrillo Marta, Resino Salvador, Briz Verónica

Abstract excerpt

Resistance-associated substitutions (RASs) to the new HCV NS5A inhibitor elbasvir may limit its efficacy and lead to virological failure in HCV-GT1a-infected patients. There are no data outside clinical trials evaluating their prevalence and impact in grazoprevir/elbasvir in GT1a-infected patients in Spain. A multicentre cross-sectional study of 632 initial patients was conducted. In 13 of these patients, the...

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Identifiers

PMID: 28521955
DOI: 10.1016/j.eimc.2017.03.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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