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Article

Low frequency of NS5A relevant resistance-associated substitutions to Elbasvir among hepatitis C virus genotype 1a in Spain: a cross-sectional study.

Scientific reports - 6 Jun 2017

Palladino Claudia, Sánchez-Carrillo Marta, Mate-Cano Irene, Vázquez-Morón Sonia, Jimenez-Sousa Ma Ángeles, Gutiérrez-Rivas Mónica, Resino Salvador, Briz Verónica

Abstract excerpt

Relevant resistance-associated substitutions (RASs) to elbasvir, the new HCV NS5A inhibitor, may limit its efficacy and lead to virological failure in HCV-GT1a-infected patients. There are few data outside clinical trials evaluating their prevalence and impact of elbasvir/grazoprevir. A multicenter cross-sectional study of 617 HCV-GT1a-infected individuals attended in 84 Spanish hospitals from the 17 Autonomous...

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Identifiers

PMID: 28588311
DOI: 10.1038/s41598-017-02968-7
PMCID: PMC5460287

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Low frequency of NS5A relevant resistance-associated substitutions to Elbasvir among hepatitis C virus genotype 1a in Spain: a cross-sectional study.PMID 28588311Read ↗

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