Article
Effectiveness of elbasvir/grazoprevir plus ribavirin for hepatitis C virus genotype 1a infection and baseline NS5A resistance.
Annals of hepatology - 1 Jan 2000
Hill Deanna D, Kramer Jennifer R, Chaffin Kassie R, Mast T Christopher, Robertson Michael N, Kanwal Fasiha, Haber Barbara A
Abstract excerpt
INTRODUCTION AND OBJECTIVES: In clinical trials, patients with hepatitis C virus (HCV) genotype (GT)1a infection and baseline resistance-associated substitutions (RASs) at amino acid positions 28, 30, 31, or 93 receiving elbasvir/grazoprevir for 12 weeks achieved lower rates of sustained virologic response (SVR) than those without baseline RASs. SVR rates in patients with RASs were improved when...
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